Comparing the utility of lung function parameters and fractional exhaled nitric oxide in predicting lung cancer

Main Article Content

Hongli Cao
Emergency department, Beijing Rehabilitation Hospital, Capital Medical University, China;

Xianyang Chen
Bao Feng Key Laboratory of Genetics and Metabolism, Beijing, China.

Yige Song
Bao Feng Key Laboratory of Genetics and Metabolism, Beijing, China.

Teng Xue
Bao Feng Key Laboratory of Genetics and Metabolism, Beijing, China.

Zhongwen Xue
Emergency department, Beijing Rehabilitation Hospital, Capital Medical University, China;

Guosheng Zhang
Emergency department, Beijing Rehabilitation Hospital, Capital Medical University, China;

Kun Wang
Emergency department, Beijing Rehabilitation Hospital, Capital Medical University, China;

Zijin Liu
Orthopedics department, Beijing Rehabilitation Hospital, Capital Medical University, China

Keywords

lung cancer, clinical factors, risk factors, pulmonary function, Feno levels

Abstract

This study aimed to investigate the potential clinical factors that may be associated with the incidence of lung cancer. A total of 150 individuals were enrolled in this cohort study, of which 78 were diagnosed with lung cancer. The results of this study revealed some interesting findings. Specifically, male sex, older age, and lower BMI were found to be significantly associated with an increased risk of developing lung cancer. In contrast, several pulmonary function measures, including FEV1/FVC ratio, FVC, and FEV1, were significantly associated with a decreased risk of lung cancer. Additionally, higher levels of Feno were found to be significantly associated with an increased risk of lung cancer. These findings may be useful in developing strategies for the prevention and management of lung cancer, particularly for individuals with these risk factors. Further research is needed to validate these findings and explore the underlying mechanisms behind these associations. Overall, this study provides valuable insights into the potential clinical factors that may be associated with lung cancer incidence, and it highlights the importance of early detection and prevention strategies.

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Published
Dec 10, 2024
DOI: https://doi.org/10.36141/svdld.v41i4.14694

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1.
Cao H, Chen X, Song Y, Xue T, Xue Z, Zhang G, et al. Comparing the utility of lung function parameters and fractional exhaled nitric oxide in predicting lung cancer. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2024 Dec. 10 [cited 2025 Jan. 22];41(4):e2024065. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/14694
Issue
Vol. 41 No. 4 (2024)
Section
Original Articles: Clinical Research
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Creative Commons License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.

How to Cite

1.
Cao H, Chen X, Song Y, Xue T, Xue Z, Zhang G, et al. Comparing the utility of lung function parameters and fractional exhaled nitric oxide in predicting lung cancer. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2024 Dec. 10 [cited 2025 Jan. 22];41(4):e2024065. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/14694
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