An unusual case of sarcoidosis presenting as calf pain

An unusual case of sarcoidosis presenting as calf pain

Authors

  • Nayan Patel Sureja a:1:{s:5:"en_US";s:96:"Consultant, Department of Rheumatology and Clinical Immunology, Star Hospitals, Hyderabad, India";}
  • Meenakshi Swain Department of Pathology, Apollo Hospitals, Hyderabad, India
  • Santhi Bhushan Murari Department of Nuclear medicine, Vijaya Diagnostic Centre Limited, Hyderabad, India
  • Power Ravuri Department of Radiology and Imaging, Star Hospitals, Hyderabad, India

Keywords:

Granulomatous myositis, Myositis, Sarcoidosis

Abstract

Sarcoidosis is a multisystem chronic inflammatory disease predominantly affecting the lungs. Myositis as a presenting manifestation of sarcoidosis is extremely uncommon and seldom reported. Here we report a 20-year-old male who presented with bilateral calf pain for six months. On evaluation magnetic resonance imaging showed features of myositis, and muscle biopsy was suggestive of sarcoidosis with granulomatous vasculitis. Positron emission tomography-computed tomography scan revealed involvement of spleen in addition to the muscles. Patient was managed with corticosteroids and azathioprine, and showed good treatment response.

References

Kobak S. Sarcoidosis: a rheumatologist's perspective. Ther Adv Musculoskelet Dis. 2015;7:196-205.

Bechman K, Christidis D, Walsh S, Birring SS, Galloway J. A review of the musculoskeletal manifestations of sarcoidosis. Rheumatology (Oxford). 2018;57:777-83.

Gupta M, Duggal L, Jain N, Chintala B. Myositis as initial presentation of sarcoidosis: A rarity. Indian J Rheumatol 2020;15:226-8.

Ten Dam L, Raaphorst J, van der Kooi AJ, et al. Clinical characteristics and outcome in muscular sarcoidosis: a retrospective cohort study and literature review. Neuromuscul Disord. 2022;32:557-63.

Cohen Aubart F, Abbara S, Maisonobe T, et al. Symptomatic muscular sarcoidosis: Lessons from a nationwide multicenter study. Neurol Neuroimmunol Neuroinflamm. 2018;5:e452.

Yeboah J, Afkhami M, Lee C, Sharma OP. Necrotizing sarcoid granulomatosis. Curr Opin Pulm Med. 2012;18:493-8.

Baughman RP, Valeyre D, Korsten P, et al. ERS clinical practice guidelines on treatment of sarcoidosis. Eur Respir J. 2021;58:2004079.

Mostard RL, van Kroonenburgh MJ, Drent M. The role of the PET scan in the management of sarcoidosis. Curr Opin Pulm Med. 2013;19:538-44.

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Published

20-12-2023

Issue

Vol. 40 No. 4 (2023)

Section

Case Reports

License

Copyright (c) 2023 Nayan Patel Sureja, Meenakshi Swain, Santhi Bhushan Murari , Ravuri Power

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How to Cite

1.
Sureja NP, Swain M, Murari SB, Ravuri P. An unusual case of sarcoidosis presenting as calf pain. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2023 Dec. 20 [cited 2025 Apr. 30];40(4):e2023056. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/14004
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