Sweat gland adenocarcinoma with high serum levels of CA19-9 and CEA: difficulty in diagnosis and treatment
Keywords:
sweat gland neoplasm, CA 19-9, CEA, Eccrine ductal adenocarcinomaAbstract
Sweat gland adenocarcinoma is a rare form of adenocarcinoma of the skin. Its occurrence has been reported mainly on the scalp, upper extremities, or upper trunk. Even though it metastasizes to other major organs, we may not have difficulty in differentiating between primary lesions and metastatic lesions. Here, we will describe a 70-year-old Korean man with a diagnosis of adenocarcinoma accompanying high serum levels of CA 19-9 and CEA. PET-CT revealed multiple high glucose uptake lesions in the pancreas, lung, and submandibular gland. The final diagnosis was high grade eccrine ductal adenocarcinoma (type III) in sweat gland adenocarcinoma. The clinical course of this case was very aggressive in contrast to previously reported cases where sweat gland adenocarcinoma had a long indolent clinical course. This patient succumbed to disease progression 3 months after diagnosis.
Downloads
Published
Issue
Section
License
OPEN ACCESS
All the articles of the European Journal of Oncology and Environmental Health are published with open access under the CC-BY Creative Commons attribution license (the current version is CC-BY, version 4.0 http://creativecommons.org/licenses/by/4.0/). This means that the author(s) retain copyright, but the content is free to download, distribute and adapt for commercial or non-commercial purposes, given appropriate attribution to the original article.
The articles in the previous edition of the Journal (European Journal of Oncology) are made available online with open access under the CC-BY Creative Commons attribution license (the current version is CC-BY, version 4.0 http://creativecommons.org/licenses/by/4.0/).
Upon submission, author(s) grant the Journal the license to publish their original unpublished work within one year, and the non exclusive right to display, store, copy and reuse the content. The CC-BY Creative Commons attribution license enables anyone to use the publication freely, given appropriate attribution to the author(s) and citing the Journal as the original publisher. The CC-BY Creative Commons attribution license does not apply to third-party materials that display a copyright notice to prohibit copying. Unless the third-party content is also subject to a CC-BY Creative Commons attribution license, or an equally permissive license, the author(s) must comply with any third-party copyright notices.