Brain-stem/Tronco encefalico (C71.7) - Large medulloblastoma with brain-stem invasion in an adult: case report and review of the literature / Grande medulloblastoma con interessamento del cervello staminale in persona adulta: resoconto di un caso e revisione della letteratura
Keywords:
Medulloblastoma, PNET, posterior fossa, radiotherapy, tumor, fossa posteriore, radioterapia, tumoreAbstract
We report the case of a 43-year-old woman with a large midline medulloblastoma invading the brain-stem. She underwent a radical resection followed by radio- and chemotherapy. The follow-up period was 2.5 years; she is now without recurrence of the tumor, but neurological deficits, mostly in the form of cerebellar dysfunction, persist. The aim of this case report is to increase awareness of the incidence, treatment and prognosis of primitive neuroectodermal tumors in adults. Medulloblastomas are rare and compared to the pediatric population, have a relatively good prognosis. The most important prognostic factors are completeness of the resection and presence of metastases.Grande medulloblastoma con interessamento del cervello staminale in persona adulta: resoconto di un caso e revisione della letteratura
Riportiamo il caso di una donna di 43 anni affetta da grande midline medulloblastoma che ha invaso il cervello-staminale. È stata sottoposta a radicale resezione seguita da radio e chemioterapia. Il periodo di follow-up è stato di 2 anni e mezzo. Non ci sono state recidive del tumore ma persistono deficit neurologici, principalmente sotto forma di disfunzioni cerebellari. Attraverso il resoconto di questo caso clinico si intende aumentare la consapevolezza dell’incidenza, del trattamento e della prognosi dei tumori primitivi neuroectodermali negli adulti. I medulloblastomi sono rari e se rapportati alla popolazione pediatrica, hanno una prognosi relativamente buona. I fattori più importanti legati alla prognosi sono la completezza della resezione e la presenza di metastasi.
Downloads
Published
Issue
Section
License
OPEN ACCESS
All the articles of the European Journal of Oncology and Environmental Health are published with open access under the CC-BY Creative Commons attribution license (the current version is CC-BY, version 4.0 http://creativecommons.org/licenses/by/4.0/). This means that the author(s) retain copyright, but the content is free to download, distribute and adapt for commercial or non-commercial purposes, given appropriate attribution to the original article.
The articles in the previous edition of the Journal (European Journal of Oncology) are made available online with open access under the CC-BY Creative Commons attribution license (the current version is CC-BY, version 4.0 http://creativecommons.org/licenses/by/4.0/).
Upon submission, author(s) grant the Journal the license to publish their original unpublished work within one year, and the non exclusive right to display, store, copy and reuse the content. The CC-BY Creative Commons attribution license enables anyone to use the publication freely, given appropriate attribution to the author(s) and citing the Journal as the original publisher. The CC-BY Creative Commons attribution license does not apply to third-party materials that display a copyright notice to prohibit copying. Unless the third-party content is also subject to a CC-BY Creative Commons attribution license, or an equally permissive license, the author(s) must comply with any third-party copyright notices.