History of the first organ transplant: blood transfusions

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Karidia Karaboue


Blood transfusions, transplantations


The term transplantation refers to various situations which differ in the type of biological material involved, how it is performed and the type of donor. We usually refer to the experience of transplantation in terms of a gift that one person donates to another: the risk, however, is that this concept is used automatically, uncritically, without any prior reflection on its characteristics. The origins and development of the first type of transplantation are found in blood transfusions, and there were numerous scientific discoveries and technical innovations at the turn of the 19th and 20th centuries which enabled transfusions to become an established practice. The common thread running through this analysis is the figure of the blood donor, initially flanked by that of the paid donor, and only since 1990 recognised as the sole legitimate source of blood and its components.
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1. Zonza M. Breve storia delle pratiche trasfusionali e della donazione di sangue. La donazione in Italia, Milano: Springer; 2011.
2. Greenwalt TJ. A Short History of Transfusion Medicine. Transfusion 1997; 37(5):550–63.
3. Bernetti A, La Russa R, De Sire A, et al. Cervical Spine Manipulations: Role of Diagnostic Procedures, Effectiveness, and Safety from a Rehabilitation and Forensic Medicine Perspective: A Systematic Review. Diagnostics (Basel) 2022; 12(5):1056.
4. Genesi 9,5, La Bibbia, Milano: Edizioni Paoline; 1987.
5. Levitico 17, 14, La Bibbia, Milano: Edizioni Paoline; 1987.
6. El Ghouzzi MH, Rebibo D. Blood transfusion and residual risk. Rev Francoph Lab 2010; 426:79–83.
7. Karaboue MAA, Ferrara M, Bertozzi G, et al. To vaccinate or not: literacy against hesitancy: Vaccination hesitancy. Med Histor 2022; 6(1):e2022014.
8. Greenwalt TJ. A short history of transfusion medicine Transfusion 1997; 37(5):550–6.
9. Njah M, Noulra A, Yacoub S, et al. Tranfusion practices and attitudes. Tunis Med 2002; 80(6):306–11.
10. Giaconi C, Manetti AC, Turco S, et al. Post-mortem computer tomography in ten cases of death while diving: a retrospective evaluation. Radiol Med 2022; 127(3):318–29.
11. Pereira A, Sanz C, Tàssies D, Ramírez B. Do patient-related blood donors represent a threat to the safety of the blood supply?. Haematologica 2002; 87(4):427–33.
12. Learoyd P. The History of Blood Transfusion prior to the 20th Century – Part 1. Transfus Med 2012; 22(5):308–14.
13. Granata V, Coppola F, Grassi R, et al. Structured Reporting of Computed Tomography in the Staging of Neuroendocrine Neoplasms: A Delphi Consensus Proposal. Front Endocrinol (Lausanne) 2021; 12:748944.
14. Karaboue MAA, Milone V, La Casella GV, et al. What will our children do when we are gone? Italian legislature does not tackle the worries of parents of disabled children. Reflections on disability. Med Histor 2022; 6(1):e2022013.
15. Mazzei MA, Guerrini S, Cioffi Squitieri N. Reperfusion in non-occlusive mesenteric ischaemia (NOMI): effectiveness of CT in an emergency setting. Br J Radiol 2016; 89(1061):20150956.
16. Iacobellis F, Segreto T, Berritto D et al. A rat model of acute kidney injury through systemic hypoperfusion evaluated by micro-US, color and PW-Doppler. Radiol Med 2019; 124(5):323–30.
17. Fiorini F, Granata A, Battaglia Y, Karaboue MAA. Talking about medicine through mass media. G Ital Nefrol 2019; 36(1):2019-vol1.
18. Op Den Winkel R, Brunner F, Harder F. Blood transfusions and kidney transplantation: Selection or conditioning of recipient?. Helv Chir Acta 1980; 47(1-2):227–30.
19. Granata V, Morana G, D’Onofrio M, et al. Structured reporting of computed tomography and magnetic resonance in the staging of pancreatic adenocarcinoma: A delphi consensus proposal. Diagnostics (Basel) 2021; 11(11):2033.
20. Mazzariol B, Karaboue M, Di Luca A, Di Luca NM. Guidelines, good practices and best clinical health practices: Valuable guidance for physicians and judges?. Clin Ter 2018; 169(6):292–6.
21. Mueller-Eckhardt C. Risks in Tranfusion Therapy. Anasth Intensivther Notfallmed 1980; 15(3):179–88.
22. Cantisani V, Iannetti G, Miele V, et al. Addendum to the sonographic medical act. J Ultrasound 2021; 24(3):229–30.
23. Raos M, Nemet D, Bojanić I, et al. Collection and composition of autologous peripheral blood stem cells graft in patients with acute myeloid leukemia: Influence on hematopoietic recovery and outcome. Coll Antropol 2010; 34(1):105–15.
24. Lacasella GV, Karaboue K. Nutrition and hydration of patients in a persistent vegetative state. Progr Nutr 2022; 24(2):e2022136.
25. Lacasella GV, Karaboue K. A short history of human nutrition from prehistory to ancient civilisations. Progr Nutr 2022; 24(2):e2022135.
26. Landsteiner K. On agglutination of normal human blood. Transfusion 1961; 1:5–8.
27. Karaboue MAA, Massaro M, Lacasella G. Artificial nutrition and hydration: Bioethical and biolegal profiles: Artificial nutrition. Progr Nutr 2023; 25(2):e2023034.
28. Karaboue M, Massaro M, Karaboue K. When nutrition becomes artificial: A bioethical issue. Progr Nutr 2023; 25(2):e2023033.
29. Fantus B. The therapy of the Cook County Hospital. Journal of the American Medical Association 1937; 109:128–31.
30. Wright AE. On a Method of Determining the Condition of Blood Coagulability for Clinical and Experimental Purposes, and on the Effect of the Administration of Calcium Salts in Haemophilia and Actual or Threatened Haemorrhage: [Preliminary Communication]. Br Med J 1893; 2(1700):223–5.
31. Blundell J. Experiments on the Transfusion of Blood by the Syringe. Med Chir Trans 1818; 9:56–92.
32. Karaboue M, Casella GL, Karaboue K, Cipolloni L, Bosco MA, de Simone S. Il dibattito in Bioetica Health and disease: a multicultural dichotomy. Medicina e Morale 2023; 72(2): 207–12.
33. De Luca L, Veneziano FA, Karaboue M.Late Presenters with ST-Elevation Myocardial Infarction: A Call to Action. J Clin Med 2022; 11(17):5169.
34. Palaia G, Bossù M, Pranno N, et al. Oral Pathologies in Migrants: The Experience of the “PROTECT”. Project in 3023 Patients Appl Sci 2022;12(24):12621.
35. Zanza C, Tornatore G, Naturale C, et al. Cervical spine injury: clinical and medico-legal overview. Radiol Med 2023; 128(1):103–12.
36. Russo A, Reginelli A, Lacasella GV, et al. Clinical Application of Ultra-High-Frequency Ultrasound. J Pers Med 2022; 12(10):1733.
37. Cappabianca P, Russo GM, Atripaldi U, et al. Universal Access to Advanced Imaging and Healthcare Protection: UHC and Diagnostic Imaging. Med Sci (Basel) 2021; 9(4):61.