Choroidal Nodules in Ocular Sarcoidosis

Choroidal Nodules in Ocular Sarcoidosis

Authors

  • Stéphane Abramowicz Department of Ophthalmology, Hôpital Universitaire Pitié-Salpêtrière, Sorbonne Université, 47-83 Boulevard de l’Hôpital, 75013, Paris, France
  • Michel Wassef Department of Pathology, Hôpital Lariboisière, Université Paris Diderot, 2 Rue Ambroise Paré, 75010, Paris, France
  • Sara Touhami Department of Ophthalmology, Hôpital Universitaire Pitié-Salpêtrière, Sorbonne Université, 47-83 Boulevard de l’Hôpital, 75013, Paris, France

Keywords:

Sarcoidosis, Uveitis, Choroid

Abstract

Background and aim: Ocular sarcoidosis is present in 30-60% of all sarcoidosis patients. Our purpose is to increase awareness of the various presentations of ocular sarcoidosis. Methods: Short image-based clinical case report. Results: We report on a case of ocular sarcoidosis presenting with unilateral choroidal nodules in a middle-aged man. Sarcoid uveitis is generally bilateral and rather symmetrical. However, choroidal nodules are an exception to this rule, as they generally arise unilaterally. Choroidal nodules are highly responsive to oral corticosteroids. When left untreated, they may evolve to chorioretinal atrophy and secondary choroidal neovascularization. Conclusions: Knowledge of this presentation of ocular sarcoidosis can help clinicians optimize treatment outcomes for patients.

References

Sève P, Jamilloux Y, Tilikete C, Gerfaud-Valentin M, Kodjikian L, El Jammal T. Ocular Sarcoidosis. Semin Respir Crit Care Med 2020 Oct;41(5):673-688.

Hage DG, Wahab CH, Kheir WJ. Choroidal sarcoid granuloma: a case report and review of the literature. J Ophthalmic Inflamm Infect 2022 Sep 29;12(1):31.

Baughman RP, Lower EE, Ingledue R, Kaufman AH. Management of ocular sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis. 2012 Mar;29(1):26-33.

Marquet A, Chapelon-Abric C, Maucort-Boulch D, et al. Efficacy and safety of TNF antagonists in ocular sarcoidosis: data from the French registry STAT. Sarcoidosis Vasc Diffuse Lung Dis. 2017;34(1):74-80.

Fardeau C, Herbort CP, Kullmann N, Quentel G, LeHoang P. Indocyanine Green Angiography in Birdshot Chorioretinopathy. Ophthalmology 1999 Oct;106(10):1928-34.

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Published

20-12-2023

Issue

Section

Images in Sarcoidosis

How to Cite

1.
Abramowicz S, Wassef M, Touhami S. Choroidal Nodules in Ocular Sarcoidosis. Sarcoidosis Vasc Diffuse Lung Dis [Internet]. 2023 Dec. 20 [cited 2025 Apr. 30];40(4):e2023039. Available from: https://mattioli1885journals.com/index.php/sarcoidosis/article/view/15122