Impact of the exercise on the Gut microbiota and short-chain fatty acids (SCFAs) production


  • Mashael W. Alruways Department of Clinical Laboratory Sciences, College of Applied Medical Sciences, Shaqra University, Shaqra Saudi Arabia.



SCFAs, gut microbiota, exercise, athlete health.


Gut microbiota plays an important role in the regulation of metabolic, endocrine, and immune functions. Many researchers have tried their best to demonstrate the involvement of gut microbiota in the modulation of several biochemical pathways which are connected to gut brain axis. Short chain fatty acids (SCFAs) are the vital metabolites which are produced in the colon via bacterial fermentation of dietary fibers and resistant to starch. The breakdown of dietary fibers and the subsequent fermentation of monosaccharides to SCFAs is on the most polemically discussed mechanisms of how gut bacteria influence host physiological environment. These SCFAs play an important role in gut microbiota. Fibers reduce energy density of the diet and the resulting SCFAs promote intestinal gluconeogenesis, incretin formation and afterward satiety. SCFAs also deliver energy to the host and support gluconeogenesis. In this study, we aimed to assess SCFAs as a metabolic regulator and how they might enhance endurance performance in athletes. Future research may provide the usefulness of SCFAs and allowing athletes to maximize their performance in various competitions.



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