Weight loss and body composition change among workers undergoing a meal replacement dietary program: feasibility and efficacy

Weight loss and body composition change among workers undergoing a meal replacement dietary program: feasibility and efficacy

Authors

  • Luisella Vigna Dipartimento di Medicina Preventiva, Servizio di Promozione della Salute dei Lavoratori, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico via F. Sforza 35, 20122 Milan, Italy
  • A Cossovich Servizio di Promozione Salute Lavoratori, IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
  • C Barberi Servizio di Promozione Salute Lavoratori, IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
  • D Sommaruga Servizio Dietetico Direzione Sanitaria di Presidio, IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
  • L Neri Servizio di Promozione Salute Lavoratori, IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
  • D Conti Servizio di Promozione Salute Lavoratori, IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
  • F De Simone UO Biochimica Clinica, Fondazione IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
  • GM Agnelli Servizio di Promozione Salute Lavoratori, IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy
  • L Riboldi Servizio di Promozione Salute Lavoratori, IRCCS Ca Granda Ospedale Maggiore Policlinico, Milano, Italy

Keywords:

Weight Loss, Dietary Intervention, Energy Intake, Low-Carbs Diet

Abstract

Introduction. Partial meal replacements supplementing low calorie diets may be convenient for working people in time-constrained occupational settings. However, there is limited data obtained among non-obese, otherwise healthy subjects and very few real-life clinical studies corroborating findings from clinical experiments.

Methods. We evaluated weight loss, glycemic control and body composition change among volunteer workers undergoing a 4-week low calorie diet followed by a 4-week maintenance regimen supplemented with meal replacements products.

Results. Forty-two employees took part to the study and completed the 4-week intervention, whereas 36 completed the maintenance phase. Thirty-one patients (73.7%) experienced a weight loss greater than 3% of initial body mass. There was a reduction in serum glucose (Δ28d= -6.9 mg/dL, p<0.01), insulin resistance (Δ28d= -0.40, p<0.01), insulin (Δ28d= -1.54 pmol l−1, p<0.05), and fatty mass (Δ28d= -2.2%, p<0.01) after adjustment for potential confounders. There was negligible reduction in lean body mass (Δ28d=-0.3%, Δ60d=-0.2%; p for trend =0.54) and basal metabolic rate (Δ28d=-8.0, Δ60d=-6.0; p for trend =0.44).  

Conclusions. We observed significant weight loss during a 2-month intervention period. The dietary strategy was well accepted irrespective of age, dietary regimen and sex. We also observed a improvement in glycemic control, both among overweight and normal weight volunteers.

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Published

30-09-2016

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Section

Original articles

How to Cite

1.
Vigna L, Cossovich A, Barberi C, Sommaruga D, Neri L, Conti D, et al. Weight loss and body composition change among workers undergoing a meal replacement dietary program: feasibility and efficacy. Progr Nutr [Internet]. 2016 Sep. 30 [cited 2025 Mar. 4];18(3):213-21. Available from: https://mattioli1885journals.com/index.php/progressinnutrition/article/view/5583

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