Antihyperglycemic and antihyperlipidemic effects of olive and fenugreek leaves in alloxan-induced diabetic rats

Abstract

This study was performed to evaluate the glucose and lipid - lowering effects of Olive leaves (OL) and Fenugreek leaves (FL) on diabetic rats. Forty-eight healthy albino rats were injected with alloxan inducing hyperglycemia except normal control group then diabetic rats randomly divided into eight groups. Two groups are normal control and diabetic control. Six diabetic groups were fed on basal diet containing different levels 2.5%, 5% and 7.5% OL and FL respectively. Results revealed that consuming diet containing 7.5% OL and 7.5% FL lowers serum glucose level by 28.3% and 21.68% respectively and restoring all biochemical parameters to near normal levels, from another hand with elevating serum Ca & P intracellular storing levels by (17.3% and 20.1%) and (22.7% and 23.8%) for 5% FL and 5% OL respectively as compared to (+) control group.