A Study About The Effect of Type-II Collagen on Balance Performance in Women With Knee Osteoarthritis

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Cengiz Taşkın
Ali Kemal TAŞKIN
Ümmühan TÜMKAYA
Ercan YAMAKOĞLU
Cevdet Can DELİHACIOĞLU
Mehmet YILMAZ

Keywords

Osteoarthritis, Collagen, Balance

Abstract

In this study, the effect of hydrolyzed type-II collagen supplementation on Y balance performance investigated in patients with stage 2-3 osteoarthritis according to Kellgren Lawrence radiological staging. A total of 20 female patients that consists of 10 experimental groups with a average age of 38.7 ± 2.70 and 10 control groups with a average age of 38.3 ± 1.99 were included in the study. Tthe experimental group patients received paracetamol treatment with 1500 mg/day for three months orally hydrolyzed type-II collagen treatment on an empty stomach 10 g/day in the morning. The patients in the control group received only 1500 mg/day paracetamol treatment for three months. As a result of the statistical analysis that is performed at the end of the study, it is found that there are statistically significant differences in the Y balance’s pre-test and post-test performance values of the experimental group (p <0.05). However, there is no significant difference in the pre-test and post-test performance values of the control group (p> 0.05). As a result, it can be said that type-II collagen supplementation, which is one of the building blocks of joint cartilage in the body, can provide positive effects on the balance performance of female patients with knee osteoarthritis.

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References

David C. Crowley1, Francis C. Lau2, Prachi Sharma1, Malkanthi Evans1, Najla Guthrie1, Manashi Bagchi2, Debasis Bagchi2,3, Dipak K. Dey4, Siba P. Raychaudhuri Safety and efficacy of undenatured type II collagen in the treatment of osteoarthritis of the knee: a clinical trial 2009; 6(6):312-321

Deparle LA, Gupta RC, Canerdy TD, Goad JT, D'Altilio M,Bagchi M, Bagchi D. Efficacy and safety of glycosylated undenatured type-II collagen in therapy of arthritic dogs. J Vet Pharmacol Ther 2005; 28(4):385-90.

Denver., 2006. New Study Finds Key Role for Collagen Hydrolysate in Managing Chronic Joint Symptoms. Academic Journals & Books at Questia Online Library, German.

Dıracoğlu, D., Aydın, R., Baskent, A. ve Celik, A. (2005). Effect of kinesthesia and balance exercises in knee osteoarthritis. Journal of Rheumatology, 11(6), 303-310.

Egloff C, Hügle T, Valderrabano V. Biomechanics and pathomechanisms of osteoarthritis. Swiss Med Wkly 2012; 142: 13583.

Engquist KD, Smith CA, Chimera NJ, Warren. (2015). Performance comparison of student-athletes and general college students on the functional movement screen and the Y balance test. J Strength Cond. Res. 29(8), 2296-2303.

Evcik D. Babaoğlu Ü. S. 2007. Osteoartrit Etyopatojenezi. İç:Sarıdoğan M.editör. Osteoartrit.İstanbul:Nobel Tıp Kitapevler. S.51.

Foley, S.J., Lord, S.R., Srikanth, V., Cooley, H. ve Jones, G. (2006). Falls risk is associated with pain and dysfunction but not radiographic osteoarthritis in older adults: Tasmanian Older Adult Cohort Study. Osteoarthritis and Cartilage, 14, 533-539.

Hassan, B.S., Mockett, S. ve Doherty, M. (2001). Static postural sway, proprioception, and maximal voluntary quadriceps contraction in patients with knee osteoarthritis and normal control subjects. Annals of the Rheumatic Diseases, 60, 612-618.

Hedbom E, Hauselmann HJ. Molecular aspects of pathogenesis in osteoarthritis: the role of inflammation. Cell Mol Life Sci. 2002; 59: 45-53.

Kawcak CE. Frisbie DD. Effects of exercise vs. experimental osteoarthritis on imaging outcomes. Osteoarthritis Cartilage, 2008 Dec; 16 (12) ; 1519-25.

Koçyigit BF, Koca TT. Neuropathic pain adversely affects functional status, quality of life, and depression in patients with knee osteoarthritis. Ortadogu Tıp Derg 2019; 1: 15-21.

Loeser, R.F. ve Shakoor, N. (2003). Aging or osteoarthritis: which is the problem? Rheumatic Disease Clinics of North America, 29, 653-673.

Mankin HJ. Clinical Features of Osteoarthritis in Textbook of Rheumatology. Kelly HR (Ed), Stage, fourth. Edit. Philadelphia: WB. Saunders Company, 1993; 1374-1399.

McAlindon, T.E., Cooper, C., Kirwan, J.R. ve Dieppe, P.A. (1993). Determinants of disability in osteoarthritis of the knee. Annals of the Rheumatic Diseases, 52, 258-262.

Moskowitz, R., 2000. Role of collagen hydrolysate in bone and joint disease. Seminars in Arthritis and Rheumatism 30 (2): 87-99.

M Scarpellini, A Lurati, G Vignati, M G Marrazza, F Telese, K Re, A Bellistri. Biomarkers, type II collagen, glucosamine, and chondroitin sulfate in osteoarthritis follow-up: the "Magenta osteoarthritis study" Journal of Orthopaedics and Traumatology 2008; 9(2):81-7.

Reijman M, Hazes JM, Bierma-Zeinstra SM. A new marker for osteoarthritis: cross-sectional and longitudinal approach. Arthritis Rheum 2004; 50:2471–2478

Robinson, R., & Gribble, P. (2008). Kinematic predictors of performance on the Star Excursion Balance Test. Journal of sport rehabilitation, 17(4), 347-357.

Sütbeyaz, S.T., Sezer, N., Köseoğlu, B.F., İbrahimoğlu, F. ve Tekin, D. (2007). Influence of knee osteoarthritis on exercise capacity and quality of life in obese adults. Obesity (Silver Spring, MD) 15(8), 2071-2076

Toprak, R. (2003). Yorgunluk ve Osteoartritin Diz Propriosepsiyonuna Etkisi. Fiziksel Tıp ve Rehabilitasyon Anabilim Dalı Uzmanlık Tezi, Başkent Üniversitesi, Ankara.

Tüzün F, Eryavuz M, Akarırmak Ü. Hareket Sistemi Hastalıkları. İstanbul: Nobel Tıp Kitabevleri, 1997: 109-113.

Yıldırım MA, Ones Kadriye, Goksenoglu G. Assessment of the frequency of neuropathic pain in knee osteoarthritis and its relation to a functional state, quality of life, and depression. J PMR Sci 2019; 22(3): 102-7.