Effect of the comprehensive intervention of exercise and diet on obese patients

Main Article Content

Pengju Jia
Fang Wang

Keywords

exercise, diet, obese patients, intervention, fasting blood glucose, lipid

Abstract

Objective: This study aims to analyze the effect of comprehensive intervention of exercise and diet on the body weight of obese patients. Methods: Forty obese patients were selected as subjects. A comprehensive intervention method of exercise and diet for eight weeks was designed. The body indexes (body weight, body mass index (BMI), etc.) and blood indexes (fasting blood glucose, total cholesterol, etc.) were measured and compared before intervention and four and eight weeks after intervention. Results: There was no significant difference between male and female patients. Compared to before intervention, after eight weeks of intervention, the weight of patients decreased significantly (p < 0.05), the BMI, waist to hip ratio (WHR), and percentage of body fat (PBF) significantly decreased (p < 0.05), the fasting blood glucose decreased (p < 0.05), the blood lipid level also significantly reduced, and the blood urea nitrogen had no significant change. Conclusion: The comprehensive intervention of exercise and diet has a significant effect on weight loss and fat reduction of obese patients, which is beneficial to improve the blood glucose and blood lipid levels of patients.

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References

[1] de Barros F, Setúbal S, Martinho JM, Ferraz L, Gaudêncio A. Correlation of non-alcoholic fatty liver disease and features of metabolic syndrome in morbidly obese patients in the preoperative assessment for bariatric surgery. Arq Bras Cir Dig 2016; 29: 260-263.
[2] Côté-Daigneault J, Leclerc P, Joubert J, Bouin M. High prevalence of esophageal dysmotility in asymptomatic obese patients. Can J Gastroenterol Hepatol 2016; 28: 311-314.
[3] Gómez-Serrano M, Camafeita E, García-Santos E,et al. Proteome-wide alterations on adipose tissue from obese patients as age-, diabetes- and gender-specific hallmarks. Sci Rep 2016; 6: 25756.
[4] Chuang JF, Rau CS, Kuo PJ, et al. Traumatic injuries among adult obese patients in southern Taiwan: a cross-sectional study based on a trauma registry system. BMC Public Health 2016; 16: 275.
[5] Leonard KL, Davies SW, Waibel BH. Perioperative Management of Obese Patients. Surg Clin N Am 2015; 95: 379-390.
[6] Ngandu T, Lehtisalo J, Solomon A, et al. A 2 year multidomain intervention of diet, exercise, cognitive training, and vascular risk monitoring versus control to prevent cognitive decline in at-risk elderly people (FINGER): a randomised controlled trial. Lancet 2015.
[7] Hui A, Back L, Ludwig S, et al. Lifestyle intervention on diet and exercise reduced excessive gestational weight gain in pregnant women under a randomised controlled trial. BJOG: Inte J Obstet Gy 2015; 119: 70-77.
[8] Mcpherson NO, Owens JA, Fullston T, Lane M. Preconception diet or exercise intervention in obese fathers normalizes sperm microRNA profile and metabolic syndrome in female offspring. Am J Physiol - Endoc M 2015; 308: E805.
[9] Pogacnik Murillo AL, Eckstein F, Wirth W, et al. Impact of Diet and/or Exercise Intervention on Infrapatellar Fat Pad Morphology: Secondary Analysis from the Intensive Diet and Exercise for Arthritis (IDEA) Trial. Cells Tissues Organs 2017; 203: 258-266.
[10] Monzo-Beltran L, Vazquez-Tarragón A, Cerdà C, et al. One-year follow-up of clinical, metabolic and oxidative stress profile of morbid obese patients after laparoscopic sleeve gastrectomy. 8-oxo-dG as a clinical marker. Redox Biol 2017; 12: 389-402.
[11] Buchs NC, Azagury DE, Pugin F, et al. Roux-en-Y gastric bypass for super obese patients: what approach?. Int J Med Robot 2016; 12: 276-282.
[12] Schmatz R, Bitencourt MR, Patias LD, et al. Evaluation of the biochemical, inflammatory and oxidative profile of obese patients given clinical treatment and bariatric surgery. Clin Chim Acta 2016; 465: 72-79.
[13] Camastra S, Vitali A, Anselmino M, et al. Muscle and adipose tissue morphology, insulin sensitivity and beta-cell function in diabetic and nondiabetic obese patients: effects of bariatric surgery. Sci Rep 2017; 7: 9007.