Critical Issues in Assessing Occupational Exposure to Diesel Dust Exhaust

Authors

  • Giuseppina Folesani Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL - Italian Workers’ Compensation Authority, Via Fontana Candida 1, 00078 Monte Porzio Catone, Rome, Italy https://orcid.org/0000-0001-9201-8731
  • Monica Gherardi Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL - Italian Workers’ Compensation Authority, Via Fontana Candida 1, 00078 Monte Porzio Catone, Rome, Italy
  • Maricla Galetti Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL - Italian Workers’ Compensation Authority, Via Fontana Candida 1, 00078 Monte Porzio Catone, Rome, Italy https://orcid.org/0000-0002-8061-8649
  • Pier Giorgio Petronini Department of Medicine and Surgery, University of Parma, Viale Gramsci 14, 43126 Parma, Italy; Center of Excellence for Toxicological Research (CERT) at University of Parma, Viale Gramsci 14, 43126 Parma, Italy
  • Fabrizio De Pasquale Local Health Unit AUSL Modena, SPSAL-Department of Public Health, 41121 Modena, Italy
  • Delia Cavallo Department of Occupational and Environmental Medicine, Epidemiology and Hygiene, INAIL - Italian Workers’ Compensation Authority, Via Fontana Candida 1, 00078 Monte Porzio Catone, Rome, Italy https://orcid.org/0000-0002-2331-1464
  • Massimo Corradi Department of Medicine and Surgery, University of Parma, Viale Gramsci 14, 43126 Parma, Italy. 3Center of Excellence for Toxicological Research (CERT) at University of Parma, Viale Gramsci 14, 43126 Parma, Italy. Center of Excellence for Toxicological Research (CERT) at University of Parma, Viale Gramsci 14, 43126 Parma, Italy

Keywords:

diesel engine exhaust, particulate matter, elemental carbon, black carbon, occupational exposure

Abstract

The Italian Interministerial Decree of February 11, 2021, introduces the diesel engine exhaust (DDE) among the carcinogenic occupational compounds, also establishing an occupational exposure limit. Elemental carbon (EC), improperly called black carbon, has been proposed as a tracer of DDE exposure; EC is the carbon that is quantified in the ambient matrixes after all the organic carbon has been removed; traditionally, EC is measured with a thermo-optical analytical technique. EC determination and relative interpretation are challenging for the following reasons: (i) the scarce availability of equipped laboratories hampers EC analysis, (ii) EC interpretation is not easy due to the lack of reference values. Finally, (iii) the limit value of 0.050 mg/m3 of EC in the workplace appears too high compared to recently published exposure data. All these aspects stimulate a reflection on the significance of EC data in the context of both occupational hygiene and occupational medicine.

References

Dewis DW, Asme. ICR350-A TURBINE SOLUTION FOR MEDIUM AND HEAVY DUTY VEHICLES. Proceedings of the Asme Turbo Expo 2011, Vol 3. 2012:823-832

IARC Monographs. Exposure as a firefighter. 2023

Silverman DT, Bassig BA, Lubin J, et al. The Diesel Exhaust in Miners Study (DEMS) II: Temporal Factors Related to Diesel Exhaust Exposure and Lung Cancer Mortality in the Nested Case-Control Study. Environ Health Perspect. Aug 2023;131(8):87002. Doi:10.1289/EHP11980

IARC Monographs. Diesel and Gasoline Engine Exhausts and some Nitroarenes. 2013

Roadmap on Carcinogens. The facts on diesel engine exhaust. Available on line: https://roadmaponcarcinogens.eu/dieselexhaust (accessed on 7 February 2024)

International Labour Office (ILO). Exposure to hazardous chemicals at work and resulting health impacts: A global review. Geneva, Switzerland 2021

Ministero del Lavoro e Politiche Sociali Ministero della Sanità. Decreto Interministeriale 11 Febbraio 2021. GU Serie Generale n 44 del 22 2 2021

European Parliament. Directive (EU) 2019/130 of 16 January 2019 amending Directive 2004/37/EC on the protection of workers from the risks related to exposure to carcinogens or mutagens at work.

Decreto Legislativo 44/2020. Attuazione della direttiva (UE) 2017/2398 del Parlamento europeo e del Consi-glio, del 12 dicembre 2017, che modifica la direttiva 2004/37/CE del Consiglio, relativa alla protezione dei la-voratori contro i rischi derivanti da un'esposizione ad agenti cancerogeni o mutageni durante il lavoro. GU (Serie Generale) n°145 del 9 Giugno 2020.

Garshick E, Laden F, Hart JE, Davis ME, Eisen EA, Smith TJ. Lung cancer and elemental carbon exposure in trucking industry workers. Environ Health Perspect. Sep 2012;120(9):1301-6. Doi:10.1289/ehp.1204989

European Commission. SCOEL/OPIN/403. Diesel Engine Exhaust. Scientific Committee on Occupational Exposure

Limits; Adopted 21 December 2016. https://data.europa.eu/doi/10.2767/299599

AIDII, Associazione Italiana Igienisti Industriali, ente terzo settore. Esposizione occupazionale a emissioni di gas di scarico dei motori diesel. 30/03/2023:4. www.aidii.it

Schauer JJ. Evaluation of elemental carbon as a marker for diesel particulate matter. J Expo Anal Environ Epi-demiol. Nov 2003;13(6):443-53. Doi:10.1038/sj.jea.7500298

Kim J, Peters CE, Arrandale VH, et al. Burden of lung cancer attributable to occupational diesel engine exhaust exposure in Canada. Occupational and Environmental Medicine. Sep 2018;75(9):617-622. Doi:10.1136/oemed-2017-104950

Richiardi L, Mirabelli D, Calisti R, et al. Occupational exposure to diesel exhausts and risk for lung cancer in a population-based case-control study in Italy. Annals of Oncology. Dec 2006;17(12):1842-1847. Doi:10.1093/annonc/mdl307

Diaz-Sanchez D, Riedl M. Diesel effects on human health: a question of stress? American Journal of Physiolo-gy-Lung Cellular and Molecular Physiology. Nov 2005;289(5):L722-L723. Doi:10.1152/ajplung.00217.2005

Sorokina AS, Burov EA, Koshelev VN, Ivanova LV, Shaidullina GM, Rakov DV. Chromatographic Methods of In-vestigation of Hydrocarbon Composition of Diesel Fuels. Chemistry and Technology of Fuels and Oils. Nov 2021;57(5):770-776. Doi:10.1007/s10553-021-01305-z

Resitoglu IA, Altinisik K, Keskin A. The pollutant emissions from diesel-engine vehicles and exhaust after-treatment systems. Clean Technologies and Environmental Policy. Jan 2015;17(1):15-27. Doi:10.1007/s10098-014-0793-9

Twigg MV, Phillips PR. Cleaning the Air We Breathe - Controlling Diesel Particulate Emissions from Passenger Cars. Platinum Metals Review. Jan 2009;53(1):27-34. Doi:10.1595/147106709x390977

Schneider C.G. and Hill L.B. Diesel and Health in America: The Lingering Threat. Clean Air Task Force. 2005. www.catf.us

Kristensen K. Air Pollution in Airports Ultrafine particles, solutions and succesful cooperation. The Danish Ecocouncil. www.ecocouncil.dk; 2012.

OSHWIKI. European Agency for Safety and Health at Work. Exposure to dusts and aerosols-diesel exhaust. Last update 21/10/2020.

Piia Taxell TS. 149. Diesel Engine Exhaust. ARBETE OCH HALSA SCIENTIFIC SERIAL. UNIVERSITY OF GOTHENBURG. 2016.

IARC. IARC:DIESEL ENGINE EXHAUST CARCINOGENIC. Press Release N°213, June 12, 2012.

Rosner G. Diesel fuel and exhaust emissions. Geneva: World Health Organization; 1996

Lim J, Lim C, Jung S. Characterizations of Size-segregated Ultrafine Particles in Diesel Exhaust. Aerosol and Air Quality Research. 2021;21(5):200356. Doi:10.4209/aaqr.200356

NIOSH, National Institute for Occupational Safety and Health. NIOSH Manual of Analytical Methods (NMAM), 5th Edition. 2020

Kwon HS, Ryu MH, Carlsten C. Ultrafine particles: unique physicochemical properties relevant to health and disease. Experimental and Molecular Medicine. Mar 2020;52(3):318-328. Doi:10.1038/s12276-020-0405-1

UNI EN 14530:2005. Atmospheres in the Workplace - Determination of Diesel Particulate Matter - General Requirements

UNI EN 481:1994 Atmosphere in the work environment. Definition of particle size fractions for the meas-urement of airborne particles

UNI EN 16909:2017. Ambient Air - Determination of elemental carbon (EC) and organic carbon (OC) depos-ited on filters

UNI EN 12341:2014. Ambient Air - Gravimetric reference method for the determination of the mass concen-tration of suspended particulte matter PM10 or PM2.5

ISO 18158:2016. Workplace air - Terminology

Ramachandran G, Watts WF. Statistical comparison of diesel particulate matter measurement methods. Aiha Journal. May-Jun 2003;64(3):329-337

Pronk A, Coble J, Stewart PA. Occupational exposure to diesel engine exhaust: A literature review. Journal of Exposure Science and Environmental Epidemiology. Jul-Aug 2009;19(5):443-457. Doi:10.1038/jes.2009.21

Decreto Ministeriale 05/5/2015 GU, Allegato I. Metodo di campionamento e di analisi per la misura delle concentrazioni di massa totale e per speciazione chimica del materiale particolato PM10 e PM 2.5

Viana Mar QX, Alastuey Andres, Reche Cristina, Favez Olivier, Malherbe Laure, Ustache Aurelien, Bartonova Alena, Liu Hai-Ying, Guerriero Cristina. Particle number (PNC) and black carbon (BC) in European urban air quality networks. 2012

Birch ME, Cary RA. Elemental carbon-based method for monitoring occupational exposures to particulate die-sel exhaust. Aerosol Science and Technology. Oct 1996;25(3):221-241. Doi:10.1080/02786829608965393

Ambient air quality and cleaner air for Europe. European Parliament legislative resolution of 24 April 2024 on the proposal for a directive of the European Parliament and of the Council on ambient air quality and cleaner air for Europe. European Parliament 24 April 2024.

WHO Global Air Quality Guidelines. Particulates (PM2,5 and PM10), ozone, nitrogen dioxide, sulphur diox-ide and carbon monoxide. ISBN 978-92-4-003422-8 (electronic version). World Health Organization 2021.

Proposal for a Directive of the European Parliament and of the Council on ambient air quality and cleaner air for Europe. Brussels, 26 10 2022

Janssen Nicole AH G-NME, Lanki Timo, Salonen Raimo O, Cassee Flemming, Hoek Gerarad, Fischer Paul, Brunekreef Bert, Krzyzanowski Michal. Health Effects of Black Carbon. 2012

Andersen ZJ, Gehring U, De Matteis S, et al. Clean air for healthy lungs - an urgent call to action: European Respiratory Society position on the launch of the WHO 2021 Air Quality Guidelines. European Respiratory Journal. Dec 2021;58(6)2102447. Doi:10.1183/13993003.02447-2021

Niranjan R, Thakur AK. The Toxicological Mechanisms of Environmental Soot (Black Carbon) and Carbon Black: Focus on Oxidative Stress and Inflammatory Pathways. Frontiers in Immunology. Jun 2017;8763. Doi:10.3389/fimmu.2017.00763

Rider CF, Carlsten C. Air pollution and DNA methylation: effects of exposure in humans. Clinical Epigenetics. Sep 2019;11(1)131. Doi:10.1186/s13148-019-0713-2

Lack DA, Moosmüller H, McMeeking GR, et. al. Characterizing elemental, equivalent black, and refractory black carbon aerosol particles: a review of techniques, their limitations and uncertainties. Anal Bioanal Chem. 2014; 406:99–122. Doi: 10.1007/s00216-013-7402-3

Regione Emilia-Romagna. Piano Regionale della Prevenzione 2021-2025. Buone pratiche per la riduzione e il contenimento dell'esposizione a gas di scarico diesel nelle attività di autofficina. 2023

Plato N, Lewné M, Gustavsson P. A historical job-exposure matrix for occupational exposure to diesel exhaust using elemental carbon as an indicator of exposure. Arch Environ Occup Health. 2020;75(6):321-332. Doi:10.1080/19338244.2019.1644277

Perrino C, Catrambone M, Canepari S. Chemical Composition of PM10 in 16 Urban, Industrial and Background Sites in Italy. Atmosphere. May 2020;11(5)479. Doi:10.3390/atmos11050479

Di Ianni A, Costabile F, Barnaba F, et al. Black Carbon Aerosol in Rome (Italy): Inference of a Long-Term (2001-2017) Record and Related Trends from AERONET Sun-Photometry Data. Atmosphere. Mar 2018;9(3)81. Doi:10.3390/atmos9030081

ARPAE. Agenzia per la Prevenzione l'Ambiente e l'Energia dell'Emilia Romagna. La qualità dell'aria in Emi-lia Romagna. Edizione 2023

Sandrini S, Fuzzi S, Piazzalunga A, et al. Spatial and seasonal variability of carbonaceous aerosol across Italy. Atmospheric Environment. Dec 2014;99:587-598. Doi:10.1016/j.atmosenv.2014.10.032

Vermeulen R, Portengen L. How serious are we about protecting workers health? The case of diesel engine exhaust. Occup Environ Med. Aug 2022;79(8):540-542. Doi:10.1136/oemed-2021-107752

Vermeulen R, Silverman DT, Garshick E, Vlaanderen J, Portengen L, Steenland K. Exposure-Response Esti-mates for Diesel Engine Exhaust and Lung Cancer Mortality Based on Data from Three Occupational Cohorts. En-vironmental Health Perspectives. Feb 2014;122(2):172-177. Doi:10.1289/ehp.1306880

Downloads

Published

27-08-2024

Issue

Section

Reviews, Commentaries, Perspectives

How to Cite

1.
Folesani G, Gherardi M, Galetti M, Petronini PG, De Pasquale F, Cavallo D, et al. Critical Issues in Assessing Occupational Exposure to Diesel Dust Exhaust. Med Lav [Internet]. 2024 Aug. 27 [cited 2025 May 16];115(4):e2024029. Available from: https://mattioli1885journals.com/index.php/lamedicinadellavoro/article/view/16100