Peer review is the system used to assess the quality of a manuscript before it is published. Independent researchers in the relevant research area assess submitted manuscripts for originality, validity and significance to help editors determine whether a manuscript should be published in Acta Biomedica. Peer reviewers are experts who volunteer their time to help improve the manuscripts they review.

Acta Biomedica operates a Double-blind-system where the reviewers do not know the names of the authors, and the authors do not know who reviewed their manuscript. Reviewers are asked to express their opinion within 15 days.