Nivolumab–ipilimumab in renal cell carcinoma metastatic to the bones: A case report.

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Marilena Di Napoli
Carmela pisano
Sergio Venanzio Setola
Sisto Perdonà
Florinda Feroce
Sandro Pignata

Keywords

RCC; bone metastases; radiotherapy; PD-1; CTLA-4; immunotherapy

Abstract

In the last recent years, the introduction in the clinical setting of treatment combinations having immune checkpoint inhibitors as the backbone has dramatically improved the outcomes of patients suffering from advanced/metastatic renal cell carcinoma (RCC). Here we report the clinical course of a patient with a rapid and bulky bone recurrence of RCC after nephrectomy, experiencing long-term benefit from nivolumab–ipilimumab administered as first-line treatment.

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