Perimyocarditis as first sign of systemic onset juvenile idiopathic arthritis treated successfully with anakinra: a case-based review

Silvia Ciancia; Michela Cappella; Alessandro De Fanti; Lorenzo Iughetti

doi:10.23750/abm.v91i4.9093

Perimyocarditis as first sign of systemic onset juvenile idiopathic arthritis treated successfully with anakinra: a case-based review

Authors

Silvia Ciancia a:1:{s:5:"en_US";s:156:"Post-graduated School of Pediatrics, Department of Medical and Surgical Sciences of the Mothers, Children and Adults, University of Modena and Reggio Emilia";}
Michela Cappella Pediatric Rheumatology Unit, Santa Maria Nuova Hospital, Reggio Emilia, Italy
Alessandro De Fanti Pediatric Rheumatology Unit, Santa Maria Nuova Hospital, Reggio Emilia, Italy
Lorenzo Iughetti Postgraduate School of Pediatrics, Department of Medical and Surgical Sciences of the Mother, Children and Adults, University of Modena and Reggio Emilia, Italy

DOI: https://doi.org/10.23750/abm.v91i4.9093

Keywords:

Arthritis, Idiopathic, Juvenile, Myocarditis, Perimyocarditis, Interleukin, Anakinra

Abstract

Background: The involvement of myocardium and pericardium at the same time is very uncommon as first manifestation of juvenile idiopathic arthritis with systemic onset (soJIA).

Case: A fourteen years-old boy, referred with symptoms of acute gastroenteritis, developed a perimyocarditis as first manifestation of Still’s Disease, after only one day from the admission. The rheumatologic disease was not responding to glucocorticoid treatment. The use of anakinra was the key point of the therapy and after its administration the patient started to recover fastly.

Conclusions: This case report describes cardiac involvement as first sign of soJIA and the successful use of anakinra inducing remission of soJIA not-responding to steroid therapy.

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