Monogenic hyperlipidemias

Geraldo Krasi; Vilma Bushati; Vincenza Precone; Bernardo Cortese; Francesca Agostini; Silvia Tezzele; Mirko Baglivo; Stefano Cecchin; Barbara Aquilanti; Valeria Velluti; Giuseppina Matera; Lucilla Gagliardi; Giacinto Abele Donato Miggiano; Matteo Bertelli

doi:10.23750/abm.v90i10-S.8757

Monogenic hyperlipidemias

Authors

Geraldo Krasi MAGI Balkans, Tirana, Albania
Vilma Bushati MAGI Balkans, Tirana, Albania
Vincenza Precone MAGI Euregio, Bolzano, Italy
Bernardo Cortese Cardiac Department, San Carlo Clinic, Milan, Italy
Francesca Agostini MAGI’s Lab, Rovereto (TN), Italy
Silvia Tezzele MAGI’s Lab, Rovereto (TN), Italy
Mirko Baglivo MAGI Euregio, Bolzano, Italy
Stefano Cecchin MAGI’s Lab, Rovereto (TN), Italy
Barbara Aquilanti UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS
Valeria Velluti UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS
Giuseppina Matera UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS
Lucilla Gagliardi UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS
Giacinto Abele Donato Miggiano UOC Nutrizione Clinica, Fondazione Policlinico Universitario A. Gemelli IRCCS; Centro di Ricerche in Nutrizione Umana, Università Cattolica S. Cuore, Rome, Italy
Matteo Bertelli MAGI Euregio, Bolzano, Italy

DOI: https://doi.org/10.23750/abm.v90i10-S.8757

Keywords:

Hyperlipidemia, cholesterol, triglycerides, LDL, HDL

Abstract

Monogenic hyperlipidemias are a group of inherited disorders characterized by elevated plasma concentrations of lipids and lipoproteins. High plasma concentrations of lipids are the most frequent risk factor for cardiovascular disease. Monogenic hyperlipidemias are a minor cause with respect to multifactorial hyperlipidemias. Diagnosis is based on clinical findings and lipid panel measurements. Genetic testing is useful for confirming diagnosis and for differential diagnosis, recurrence risk calculation and prenatal diagnosis in families with a known mutation. Monogenic hyperlipidemias can have either autosomal dominant or recessive inheritance.

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Published

30-09-2019

Issue

Vol. 90 No. 10-S (2019): Cardiovascular Diseases (Part A) | Infertility and Metabolic Syndromes (Part B) - Guest Editor: Matteo Bertelli, Stefano Paolacci

Section

REVIEWS

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

Krasi G, Bushati V, Precone V, et al. Monogenic hyperlipidemias. Acta Biomed. 2019;90(10-S):47-49. doi:10.23750/abm.v90i10-S.8757

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