Relationship between diagnostic imaging features and prognostic outcomes in gastrointestinal stromal tumors (GIST)

Relationship between diagnostic imaging features and prognostic outcomes in gastrointestinal stromal tumors (GIST)

Authors

  • Ginevra Danti Department of Radiology, Careggi University Hospital, Florence, Italy
  • Gloria Addeo Department of Radiology, Careggi University Hospital, Florence, Italy
  • Diletta Cozzi Department of Radiology, Careggi University Hospital, Florence, Italy
  • Nicola Maggialetti Department of Medicine and Health Sciences “V. Tiberio”, University of Molise, Campobasso, Italy
  • Monica Marina Lanzetta Department of Radiology, Careggi University Hospital, Florence, Italy
  • Gianluca Frezzetti Department of Radiology, Careggi University Hospital, Florence, Italy
  • Antonella Masserelli Department of Radiology, Careggi University Hospital, Florence, Italy
  • Silvia Pradella Department of Radiology, Careggi University Hospital, Florence, Italy
  • Andrea Giovagnoni Department of Radiology, Università Politecnica delle Marche, Ancona, Italy
  • Vittorio Miele Department of Radiology, Careggi University Hospital, Florence, Italy

Keywords:

Gastrointestinal Stromal Tumors, Imaging Features, Computed Tomography, Prognostication System, Outcome

Abstract

Gastrointestinal stromal tumors (GISTs), the most frequent mesenchymal neoplasms of the gastrointestinal tract, are a relatively recently described entity. GISTs can occur across any age but are more common in patients older than 50 years. GISTs most commonly are in the stomach (60-70%), followed by the small intestine (20%-30%); they also rarely occur in the abdominal cavity, such as in the mesentery, the omentum and the retroperitoneum. Contrast-enhanced multi-detector computed tomography (MDCT) is the most largely used imaging modality for the localization, characterization and staging of GISTs. All patterns of enhancement on contrast-enhanced MDCT can be seen with GISTs, including hypoenhancing, isoenhancing, and hyperenhancing neoplasms. A lot of prognostication systems have been proposed for the risk stratification of GISTs. This review outlines the relationship between different diagnostic imaging features and prognostic outcomes in GISTs.

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Published

24-04-2019

How to Cite

1.
Relationship between diagnostic imaging features and prognostic outcomes in gastrointestinal stromal tumors (GIST). Acta Biomed [Internet]. 2019 Apr. 24 [cited 2024 Mar. 29];90(5-S):9-19. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/8343