Clinical manifestations, evaluation and management of hyperprolactinemia in adolescent and young girls: a brief review

Clinical manifestations, evaluation and management of hyperprolactinemia in adolescent and young girls: a brief review

Authors

  • Michail Matalliotakis Obstetrics and Gynecology Department of Venizeleio General Hospital, Heraklion, Crete, Greece
  • Ioannis Koliarakis Medical School, University of Crete, Heraklion, Greece
  • Charoula Matalliotaki Obstetrics and Gynecology Department of Venizeleio General Hospital, Heraklion, Crete, Greece
  • Alexandra Trivli Department of Ophthalmology, Konstantopouleio-Patission General Hospital, Athens, Greece
  • Eleftheria Hatzidaki Department of Neonatology and NICU of the University of Crete, Heraklion, Greece

Keywords:

hyperprolactinemia, adolescent girls, visual field defects, dopamine agonists

Abstract

Hyperprolactinemia (HPrl) is considered as a rare endocrinopathy in childhood. In children and adolescent girls, there are three major categories of HPrl causes; physiological, pathological and iatrogenic. Through hypogonadotropic hypogonadism, prolactin hypersecretion and production leads to the typical functional syndrome which is observed in female children and adolescents; delayed puberty, primary or secondary amenorrhea and/or galactorrhea. Regarding prolactinomas, clinical signs manifest with mass compression of the optic chiasm and anterior pituitary gland or prolactin hypersecretion. Targeted identification of HPrl is of significant importance for proper management and follow-up. The aim of this review is to focus on the evaluation of HPrl in adolescent and young girls. In addition, we aimed to summarize the current knowledge regarding the proper management of such cases.

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Published

23-01-2019

Issue

Section

Adolescentology

How to Cite

1.
Clinical manifestations, evaluation and management of hyperprolactinemia in adolescent and young girls: a brief review. Acta Biomed [Internet]. 2019 Jan. 23 [cited 2024 Apr. 16];90(1):149-57. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/8142

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