Non-invasive tests for the diagnosis of helicobacter pylori: state of the art

Non-invasive tests for the diagnosis of helicobacter pylori: state of the art

Authors

  • Stefano Kayali Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Rosalia Aloe Department of Pathology and Laboratory Medicine, University Hospital of Parma, University of Parma, Parma, Italy
  • Chiara Bonaguri Department of Pathology and Laboratory Medicine, University Hospital of Parma, University of Parma, Parma, Italy
  • Federica Gaiani Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Marco Manfredi Azienda USL of Reggio Emilia-IRCCS, Maternal and Child Department, Pediatric Unit, Sant’Anna Hospital, Castelnovo ne’ Monti, Reggio Emilia, Italy
  • Gioacchino Leandro National Institute of Gastroenterology “S. De Bellis” Research Hospital, Castellana Grotte, Italy
  • Fabiola Fornaroli Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Francesco Di Mario Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy
  • Gian Luigi de' Angelis Gastroenterology and Endoscopy Unit, Department of Medicine and Surgery, University of Parma, Parma, Italy

Keywords:

Helicobacter pylori, infection, urea breath test, antibodies, stool antigen, eradication, diagnosis

Abstract

Usually, non-invasive tests are the first methods for diagnosing Helicobacter pylori (HP) infection. Among these, serological test, stool antigen research and urea breath test are the most used. Antibodies anti-HP are not recommended in low prevalence population, moreover they cannot reveal an ongoing infection, but they only prove a contact with the bacterium. Also, they can persist for a long time after the eradication of the infection, therefore, they should not be used to verify the success of eradication therapy. Stool antigen research and Urea Breath Test (UBT) are useful both in diagnosis and during follow-up after eradication treatment. The stool antigen test is cheaper than Urea breath test with similar sensitivity and specificity.  Non-invasive tests are not able to diagnose the associated complications to HP infection.

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Published

17-12-2018

How to Cite

1.
Non-invasive tests for the diagnosis of helicobacter pylori: state of the art. Acta Biomed [Internet]. 2018 Dec. 17 [cited 2024 Mar. 29];89(8-S):58-64. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/7910