Flow and volume response to bronchodilator in patients with COPD

Flow and volume response to bronchodilator in patients with COPD

Authors

  • Matteo Vigna
  • Marina Aiello Department of Clinical and Experimental Medicine, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy
  • Giuseppina Bertorelli Department of Clinical and Experimental Medicine, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy
  • Ernesto Crisafulli Department of Clinical and Experimental Medicine, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy
  • Alfredo Chetta Department of Clinical and Experimental Medicine, Respiratory Disease and Lung Function Unit, University of Parma, Parma, Italy
DOI: https://doi.org/10.23750/abm.v89i3.5631

Keywords:

COPD, airflow obstruction, bronchodilation

Abstract

The response to a bronchodilator is considered as crucial to diagnose COPD and to distinguish COPD from asthma. COPD is characterized by progressive airflow obstruction that is only partly reversible, whereas asthma is associated with airflow obstruction that is often reversible either spontaneously or with treatment. In spite of the partly reversible airflow obstruction, patients with COPD may show a significant bronchodilator response both in terms of an increase in forced expiratory volume in 1 second (FEV1) or in forced vital capacity (FVC) after an adequate dose of an inhaled bronchodilator. Changes in FEV1 or FVC characterize, respectively, flow or volume response after bronchodilator administration. This overview will deal with the reversibility testing characteristics and its clinical significance in COPD patients.

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Published

08-10-2018

Issue

Vol. 89 No. 3 (2018)

Section

REVIEWS

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

1.
Vigna M, Aiello M, Bertorelli G, Crisafulli E, Chetta A. Flow and volume response to bronchodilator in patients with COPD. Acta Biomed [Internet]. 2018 Oct. 8 [cited 2024 Jul. 27];89(3):332-6. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/5631
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