Frailty as a dysruption of steroid “syncrinology” in elderly man

Frailty as a dysruption of steroid “syncrinology” in elderly man

Authors

  • Giorgio Valenti Dipartimento di Medicina Interna e Scienze Biomediche, Sezione di Gerontologia e Geriatria, University of Parma, Parma, Italy

Keywords:

Frailty, sarcopenia, elderly, DHEAS, testosterone

Abstract

In the background of the endocrinological hypothesis of aging, frailty in man can be seen as a dysruption of syncrinology, a term with which we could define the harmonized activity of steroid hormones (DHEAS, cortisol, testosterone). Such endocrine age-related modifications might promote the activation of sarcopenia, which exerts a core position in the progression of frailty in the elderly. Consequently, the use of replacement treatment in order to delay the beginning of such steroid derangement might be a suitable strategy to improve the quality of life of man, whose life length has been significantly extended.

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Published

01-03-2007

How to Cite

1.
Frailty as a dysruption of steroid “syncrinology” in elderly man. Acta Biomed [Internet]. 2007 Mar. 1 [cited 2024 Jun. 23];78(1Suppl):222-4. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/4622