Hypoglicemia related to big Haemangiopericitoma: a difficult diagnostic definition

Hypoglicemia related to big Haemangiopericitoma: a difficult diagnostic definition

Authors

  • Carmine Siniscalchi Parma University Hospital, Parma, Italy
  • Manuela Basaglia Parma University Hospital, Parma, Italy
  • Davide Cunzi Parma University Hospital, Parma, Italy
  • Simona Merla Parma University Hospital, Parma, Italy
  • Maria Mattioli Parma University Hospital, Parma, Italy
  • Nicola Gaibazzi Parma University Hospital, Parma, Italy
  • Riccardo Volpi Parma University Hospital, Parma, Italy

Keywords:

hypoglicemia, Haemangiopericitoma, IGF-1

Abstract

We describe the case of a 91 years old woman admitted to our department for dyspnea associated with drowsiness. At the admission to the Emergency Room the patient stay in a comatose state and blood tests performed showing severe hypoglycemia (38 mg/dl at admission in non diabetic patient). Anamnestic history: multifactorial anemia; frequent hospitalizations for heart failure; AMI treated with stenting; in 1986 Haemangiopericytoma resection in the right iliac region; in 2006 palliative surgery for recurrence with residual mass. Blood tests showed lower levels of insulin and normal C- peptide serum concentration in correspondence of low glucose concentration (in relation to continuous and adequate parenteral nutrition), IGF 1 and GH level was respectively suppressed (IGF1=47 ng/ml whit normal range 97-331 ng/ml) and normal/low (GH 0.43 uUI/mL whit normal range 0.06-14.00 uUI/mL).Therefore hypoglycemia appeared related to paraneoplastic production of IGF -2.

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Published

14-09-2015

How to Cite

1.
Siniscalchi C, Basaglia M, Cunzi D, Merla S, Mattioli M, Gaibazzi N, et al. Hypoglicemia related to big Haemangiopericitoma: a difficult diagnostic definition. Acta Biomed [Internet]. 2015 Sep. 14 [cited 2024 Jul. 14];86(2):189-92. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/4162