Pain management in pediatric age. An update

Pain management in pediatric age. An update


  • Lorenzo Di Sarno Department of Pediatrics. Fondazione Policlinico “A. Gemelli”, IRCCS. Largo Gemelli, 1 - 00168 Roma, Italia.
  • Antonio Gatto Department of Pediatrics. Fondazione Policlinico “A. Gemelli”, IRCCS. Largo Gemelli, 1 - 00168 Roma, Italia.
  • David Korn Department of Pediatrics. Fondazione Policlinico “A. Gemelli”, IRCCS. Largo Gemelli, 1 - 00168 Roma, Italia.
  • Valeria Pansini Department of Pediatrics. Fondazione Policlinico “A. Gemelli”, IRCCS. Largo Gemelli, 1 - 00168 Roma, Italia.
  • Antonietta Curatola Department of Pediatrics. Fondazione Policlinico “A. Gemelli”, IRCCS. Largo Gemelli, 1 - 00168 Roma, Italia.
  • Serena Ferretti Department of Pediatrics. Fondazione Policlinico “A. Gemelli”, IRCCS. Largo Gemelli, 1 - 00168 Roma, Italia.
  • Lavinia Capossela Department of Pediatrics. Fondazione Policlinico “A. Gemelli”, IRCCS. Largo Gemelli, 1 - 00168 Roma, Italia.
  • Benedetta Graglia
  • Antonio Chiaretti a:1:{s:5:"en_US";s:81:"Fondazione Policlinico Gemelli IRCCS - Università Cattolica del Sacro Cuore ROMA";}


Pain, Pain Assessment, Analgesic Drugs, Patient Controlled Analgesia, Childhood.


Differently from the adult patients, in paediatric age it is more difficult to assess and treat efficaciously the pain and often this symptom is undertreated or not treated. In children, a selection of appropriate pain assessment tools should consider the age, the cognitive level, the presence of eventual disability, the type of pain and the situation in which it is occurring. Improved understanding of developmental neurobiology and paediatric analgesic drug pharmacokinetics should facilitate a better management of childhood pain. The objective of this update is to discuss the current practice and the recent advances in pediatric pain management.  Using PubMed and the Cochrane Library we conducted an extensive literature analysis on pediatric pain assessment and commonly used analgesic agents in this kind of patients. According to our results, a multimodal analgesic regimen provides a better pain control and a functional outcome in children. Cooperation and communication among the anaesthesiologist, the surgeon and the paediatrician remains essential for successful anaesthesia and pain management in childhood.


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How to Cite

Di Sarno L, Gatto A, Korn D, Pansini V, Curatola A, Ferretti S, et al. Pain management in pediatric age. An update. Acta Biomed [Internet]. 2023 Aug. 3 [cited 2024 Jul. 23];94(4):e2023174. Available from: