Combined Cytokine Scores Assessed at Emergency Department Presentation Predicts COVID-19 Critical Illness : ED Cytokine Scores in COVID-19

Brandon Henry; Maria Helena; Isaac Cheruiyot; Stefanie Benoit; Justin Benoit; Giuseppe  Lippi

doi:10.23750/abm.v92i4.11182

Combined Cytokine Scores Assessed at Emergency Department Presentation Predicts COVID-19 Critical Illness

ED Cytokine Scores in COVID-19

Authors

Brandon Henry Cardiac Intensive Care Unit, The Heart Institute, Cincinnati Children’s Hospital Medical Center, Cincinnati, OH, USA
Maria Helena Department of Statistics, Federal University of Parana, Curitiba, Brazil
Isaac Cheruiyot School of Medicine, University of Nairobi
Stefanie Benoit Department of Pediatrics, University of Cincinnati, College of Medicine, OH, USA
Justin Benoit Department of Emergency Medicine, University of Cincinnati, Cincinnati, OH, USA
Giuseppe Lippi Section of Clinical Biochemistry, University of Verona, Verona, Italy

DOI: https://doi.org/10.23750/abm.v92i4.11182

Keywords:

Cytokines, COVID-19

Abstract

N/A

References

1. Henry BM, de Oliveira MHS, Benoit S, Plebani M, Lippi G. Hematologic, biochemical and immune biomarker abnormalities associated with severe illness and mortality in coronavirus disease 2019 (COVID-19): a meta-analysis. Clin Chem Lab Med. 2020 25;58(7):1021–8.
2. Nagant C, Ponthieux F, Smet J, Dauby N, Doyen V, Besse-Hammer T, et al. A score combining early detection of cytokines accurately predicts COVID-19 severity and intensive care unit transfer. International Journal of Infectious Diseases. 2020 Dec 1;101:342–5.
3. Lippi G, Henry BM, Hoehn J, Benoit S, Benoit J. Validation of the Corona-Score for rapid identification of SARS-CoV-2 infections in patients seeking emergency department care in the United States. Clinical Chemistry and Laboratory Medicine (CCLM). 2020 Aug 10;58(12):e311–3.
4. Henry BM, Benoit SW, Vikse J, Berger BA, Pulvino C, Hoehn J, et al. The anti-inflammatory cytokine response characterized by elevated interleukin-10 is a stronger predictor of severe disease and poor outcomes than the pro-inflammatory cytokine response in coronavirus disease 2019 (COVID-19). Clinical Chemistry and Laboratory Medicine (CCLM) [Internet]. 2020 Nov 25 [cited 2020 Nov 30];1(ahead-of-print). Available from: https://www.degruyter.com/view/journals/cclm/ahead-of-print/article-10.1515-cclm-2020-1284/article-10.1515-cclm-2020-1284.xml
5. Lippi G, Plebani M. Cytokine “storm”, cytokine “breeze”, or both in COVID-19? Clin Chem Lab Med. 2020;

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Published

02-09-2021

Issue

Vol. 92 No. 4 (2021)

Section

CORRESPONDENCE - SPECIAL COVID19

License

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by-nc/4.0) which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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How to Cite

Henry B, Helena M, Cheruiyot I, Benoit S, Benoit J, Lippi G. Combined Cytokine Scores Assessed at Emergency Department Presentation Predicts COVID-19 Critical Illness : ED Cytokine Scores in COVID-19. Acta Biomed [Internet]. 2021 Sep. 2 [cited 2024 Jul. 18];92(4):e2021248. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/11182

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