Complications related to in vitro reproductive techniques support the implementation of natural procreative technologies

Aysha Karim Kiani; Stefano Paolacci; Pietro Scanzano; Sandro Michelini; Natale Capodicasa; Leonardo D'Agruma; Angelantonio Notarangelo; Gerolamo Tonini; Daniela Piccinelli; Kalantary Rad Farshid; Paolo Petralia; Ezio Fulcheri; Pietro Chiurazzi; Corrado Terranova; Francesco Plotti; Roberto Angioli; Marco Castori; Matteo Bertelli

doi:10.23750/abm.v91i13-S.10525

Complications related to in vitro reproductive techniques support the implementation of natural procreative technologies

Authors

Aysha Karim Kiani MAGI EUREGIO, Bolzano, Italy
Stefano Paolacci MAGI'S LAB
Pietro Scanzano Director, San Giovanni Battista Hospital, Rome, Italy
Sandro Michelini Department of Vascular Rehabilitation, San Giovanni Battista Hospital, Rome, Italy
Natale Capodicasa Magi Balkans - Rare Genetic Diseases, Tirana, Albania
Leonardo D'Agruma Division of Medical Genetics, Fondazione IRCCS-Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
Angelantonio Notarangelo Division of Medical Genetics, Fondazione IRCCS-Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
Gerolamo Tonini Surgical Department, Unit of Urology, Poliambulanza Foundation, Brescia, Italy
Daniela Piccinelli Department of Mother and Child Health, Unit of Obstetrics and Gynecology, Poliambulanza Foundation, Brescia, Italy
Kalantary Rad Farshid Surgical Department, Unit of Urology, Poliambulanza Foundation, Brescia, Italy
Paolo Petralia General Director, IRCCS Giannina Gaslini Institute, Genoa, Italy
Ezio Fulcheri UOSD Fetal and Perinatal Pathology, Department of Translational Research, Laboratory Medicine, Diagnostics and Services, IRCCS Giannina Gaslini Institute, Genoa, Italy
Pietro Chiurazzi Istituto di Medicina Genomica, Università Cattolica del Sacro Cuore, Rome, Italy; UOC Genetica Medica, Fondazione Policlinico Universitario A. Gemelli, Rome Italy
Corrado Terranova Department of Obstetrics and Gynecology, University Campus Bio Medico, Rome, Italy
Francesco Plotti Department of Obstetrics and Gynecology, University Campus Bio Medico, Rome, Italy
Roberto Angioli Department of Obstetrics and Gynecology, University Campus Bio Medico, Rome, Italy
Marco Castori Division of Medical Genetics, Fondazione IRCCS-Casa Sollievo della Sofferenza, San Giovanni Rotondo (FG), Italy
Matteo Bertelli MAGI EUREGIO, Bolzano, Italy; MAGI’S LAB, Rovereto (TN), Italy; EBTNA-LAB, Rovereto (TN), Italy

DOI: https://doi.org/10.23750/abm.v91i13-S.10525

Keywords:

assisted reproductive technology, genetic infertility, NaProTechnology

Abstract

Background and aim: Infertility affects ~20% of the couples in the world. Assisted reproductive technologies (ARTs) are currently the most common treatment option for infertility. Nevertheless, ARTs may be associated with complications for mothers and/or offspring. Natural procreative technology (NaProTechnology) is a natural treatment which minimizes these risks by seeking to identify the causes of infertility to enable better treatments. This narrative review summarizes the complications related to ARTs and clarifies how the NaProTechnology approach can help ARTs to achieve better results or be used in alternative to ARTs. Methods: Data in the literature indicate that NaProTechnology is a natural approach for treating infertility. Results: The percentage of live births obtained by NaProTechnology is similar to that of ARTs. Conclusions: An extensive search for the genetic defects causing infertility or subfertility through genetic testing can help both ARTs and NaProTechnology to achieve successful pregnancies. By discovering the underlying causes of infertility, genetic tests enable better family counseling, like the implications of transmitting risk- and disease-alleles to future generations.

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