Platypnea-orthodeoxia after fibrotic evolution of SARS-CoV-2 interstitial pneumonia. A case report: Platypnea-Orthodeoxia and pulmonary fibrosis by COVID-19

Platypnea-orthodeoxia after fibrotic evolution of SARS-CoV-2 interstitial pneumonia. A case report

Platypnea-Orthodeoxia and pulmonary fibrosis by COVID-19

Authors

  • Chiara Longo UniversityHospital Parma
  • Livia Ruffini UniversityHospital Parma
  • Nicola Zanoni UniversityHospital Parma
  • Francesco Longo UniversityHospital Parma
  • Rocco Accogli UniversityHospital Parma
  • Tiziano Graziani UniversityHospital Parma
  • Alfredo Chetta

Keywords:

Platypnea, Orthodeoxia, Pulmonary fibrosis, SARS-CoV-2

Abstract

Platypnea-orthodeoxia syndrome (POS) is a clinical entity characterized by positional dyspnoea (platypnea) and arterial desaturation (orthodeoxia) that occurs when sitting or standing up and usually resolves by lying down.

POS may result from some cardiopulmonary disorders or from other miscellaneous aetiologies.

We report a case of POS in a patient after fibrotic evolution of SARS-CoV-2 interstitial pneumonia associated with pulmonary embolism. The patient did not have any evidence of an intracardiac/intrapulmonary shunt.

 

 

References

Agrawal A, Palkar A, Talwar A. The multiple dimensions of Platypnea-Orthodeoxia syndrome: A review. Respir Med. 2017; 129:31‐38.

Charan NB, Thompson WH, Carvalho P. Functional anatomy of bronchial veins. Pulm Pharmacol Ther. 2007; 20:100-103.

De Vecchis R, Baldi C, Ariano C, et al. Platypnea-orthodeoxia syndrome: Orthostatic dyspnea and possible pathophysiological substrates. Herz. 2017; 42(4):384-389.

Rodrigues P, Palma P, Sousa-Pereira L. Platypnea-orthodeoxia syndrome in review: defining a new disease? Cardiology 2012; 123(1):15–23

Lee C-H, Cheng S-T. Shortness of breath while sitting up: hepatopulmonary syndrome. CMAJ 2011; 183: 80.

Brambilla I, Pizzamiglio R. ABC dei test di funzionalità respiratoria. Masson Italia Ed Milano 1979, pp 137-141

Bajc M, Schümichen C, Grüning T, et al. EANM guideline for ventilation/perfusion single-photon emission computed tomography (SPECT) for diagnosis of pulmonary embolism and beyond. Eur J Nucl Med Mol Imaging. 2019; 46:2429-2451

Newman S, Bennett WD, Biddiscombe M et al. Standardization of Techniques for Using Planar (2D) Imaging for Aerosol Deposition Assessment of Orally Inhaled Products. Journal of Aerosol Medicine and Pulmonary Drug Delivery. 2012.S-10-S-28.

Burchell HBHHJ, Wood EH. Reflex orthostatic dyspnea associated with pulmonary hypotension. Am. J. Physiol. 1949; 159:563-564

Altman M, Robin ED. Platypnea (diffuse zone I phenomenon?) N. Engl. J. Med. 1969; 281:1347-1348

Robin ED, Laman D, Horn BR, Theodore J. Platypnea related to orthodeoxia caused by true vascular lung shunts. N. Engl. J. Med. 1976; 294:941-943

Takhar R, Biswas R, Arora A, Jain V. Platypnoea-orthodeoxia syndrome: novel cause for a known condition. BMJ Case Rep 2014. doi:10.1136/bcr-2013-201284

Tenholder MF, Russell MD, Knight E, Rajagopal KR. Orthodeoxia: a new finding in interstitial fibrosis. Am Rev Respir Dis. 1986; 136:170–173

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Published

07-09-2020

Issue

Section

CORRESPONDENCE/CASE REPORTS - SPECIAL COVID19

How to Cite

1.
Platypnea-orthodeoxia after fibrotic evolution of SARS-CoV-2 interstitial pneumonia. A case report: Platypnea-Orthodeoxia and pulmonary fibrosis by COVID-19. Acta Biomed [Internet]. 2020 Sep. 7 [cited 2024 May 25];91(3):e2020052. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/10386

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