Flow diverting devices in acute ruptured blood blister aneurysms: a three centric retrospective study

Flow diverting devices in acute ruptured blood blister aneurysms: a three centric retrospective study

Authors

  • Francesca Incandela 1. Section of Radiological Sciences, Department of Biomedicine, Neuroscience and Advanced Diagnostics, University of Palermo, Palermo, Italy
  • Giuseppe Craparo Neuroradiology Unity of diagnostic and intervention, A.R.N.A.S. Civico-Di Cristina-Benfratelli, Palermo, Italy
  • Sergio Abrignani Department of Diagnostic Radiology and Radiotherapy, Federico II University of Naples, Naples, Italy
  • Agostino Tessitore Neuroradiology Unit, A.O.U. Policlinico “G.Martino” - Messina, Italy
  • Antonio Pitrone Neuroradiology Unit, A.O.U. Policlinico “G.Martino” - Messina, Italy
  • Ferdinando Caranci Department of Diagnostic Radiology and Radiotherapy, Federico II University of Naples, Naples, Italy
  • Antonio Arrichiello Postgraduation School in Radiodiagnostics, Università degli Studi di Milano, Milan
  • Aldo Paolucci Operative Unit of Neuroradiology, Fondazione IRCCS Ca’ Granda Ospedale Maggiore Policlinico di Milano, Milan, Italy

Keywords:

flow-diverter, SAH, blister aneurysm (BBA), endovascular treatment (EVT), double antiplatelet therapy (DAPT), IIb/IIIa inhibitors.

Abstract

Background: Blood blister aneurysms (BBAs) are a rare tiny subset of intracranial aneurysms, located at the nonbranching site of an artery, representing a therapeutic challenge from both surgical and endovascular approach. Flow-diverting efficacy, by preserving flow through the parent artery, was approved for its use in unruptured cerebral aneurysms, but no consensus was reached on its use for BBAs ruptured in the acute setting. We report a multicenter experience of use of flow diversion in acute setting of ruptured BBA, to analyze the safety and efficacy of these devices. Methods: We performed a retrospective study of 6 consecutive intracranial BBAs treated with flow diverter devices (FDD) between 2018 and 2020 at 3 italian institutions. Materials, therapy used, complications, clinical and radiographic outcomes were reviewed. Results: We used different FDD, in all cases immediate change in contrast opacification at the end of the procedure was reported. Intraprocedural IIb/IIIa inhibitor agent was the major antiplatelet protocol administered. Any complications occurred. All patients showed complete BBA obliteration at 3 months follow-up. 5/6 patients achieved good clinical outcome (0–2 mRS) at 3 months, all of which were presented with low grade SAH (Hunt Hess I–III) and a lower Fisher grade. Conclusion: Our data support this endovascular technique as a safe and effective therapeutic modality for this pathology in the acute setting.

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Published

23-09-2020

How to Cite

1.
Flow diverting devices in acute ruptured blood blister aneurysms: a three centric retrospective study. Acta Biomed [Internet]. 2020 Sep. 23 [cited 2024 Mar. 29];91(10-S):e2020011. Available from: https://mattioli1885journals.com/index.php/actabiomedica/article/view/10261