Spontaneous abdominal bleeding associated with SARS-CoV-2 infection: causality or coincidence? Abdominal bleeding and SARS-CoV-2

Main Article Content

Bruno Sposato
Leonardo Croci
Maurizio Di Tomassi
Camilla Puttini
Carmela Olivieri
Mario Alessandri
Maria Cristina Ronchi
Elisa Donati
Alessio Garcea
Angelica Brazzi
Maria Giovanna Migliorini
Silvia Chigiotti
Nikolaos Nikiforakis
Tiziana Carli
Elena Canneti
Francesco Strambio
Cristina Cellini
Claudia Nardangeli
Maria Pia Allegri
Francesco Bianchi
Claudio Bettini
Marco Perruzza
Nicola Lanzarone
Lucia Valentini
Paolo Orselli
Marco Solari
Salvatore Cardaci
Marco Nofri
Giorgia Angeli
Francesca Mangani
Elio Aloia
Alessandro Lanari
Marta Corridi
Genni Spargi
Antonio Perrella
Cesira Nencioni

Keywords

COVID-19; SARS-CoV-2, bleeding, abdominal, pneumonia

Abstract

Authors present 3 cases of abdominal bleeding associated with COVID-19, representing 2.7 % of all hospitalized COVID-19 patients and hypothesize that there could be, although not very frequently, a relationship between SARS-CoV2 and bleeding. They excluded a side effect of the low molecular weight heparin therapy that all patients underwent during the course of the disease or other possible causes. Alterations of the coagulation state or a weakness of the vascular wall due to a presumed endotheliitis SARS-CoV-2 infection induced, are hypothesized by the authors. Investigation and follow-up for possible hemorrhagic problems in patients with COVID-19 is recommended. More studies are needed to understand if COVID-19 can be directly associated with bleeding.

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