Asbestosis, lung adenocarcinoma with lymphocytic infiltration, and non-Hodgkin lymphoma

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Claudio Bianchi
Tommaso Bianchi

Keywords

lung carcinoma, lymphoma non-Hodgkin, etiology, neoplasms multiple, asbestos

Abstract

Right lower lobectomy was performed in a 63-year-old man with previous occupational asbestos exposure. Histological examination showed a lung adenocarcinoma with massive stromal lymphocytic infiltration. Thirteen years after lobectomy, non-Hodgkin lymphoma was diagnosed on a liver biopsy. Involvement of lymphnodes and various organs was observed. The patient died two years after diagnosis of the lymphoma. Relevant necropsy findings included lymphoma, renal adenocarcinoma, lung asbestosis. This case suggests a possible relationship between lymphocytic infiltration of the lung tumor and subsequent development of the lymphoma.

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