Upper body subcutaneous adipose as a potential predictor for type 2 diabetes mellitus

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Andjelka Scepanovic
Slavica Vujovic, proffessor
Darko Medin, PhD


Keywords: type 2 diabetes mellitus, subcutaneous fatty tissue, biceps, triceps, abdominal, subscapular


Background/Aim: Upper body skinfold measurements show association with type 2 diabetes mellitus (DM2). Different pathogenesis mechanisms have been identified explaining the direct influence of subcutaneous adipose tissue in relation to insulin resistance. However, the precise predictive potential of the various points of the subcutaneous adipose tissue thickness in the upper body is not completely defined, partially because of strong influence of age on these parameters in older patients.

The aim of this study was to examine the predictive potential of 4 subcutaneous fatty tissue spots (i.e., biceps, triceps, abdominal and subcapsular) regarding DM2 subjects diagnosed with disease before 60 years of age.

Methods: Subcutaneous fatty tissue points (i.e., biceps, triceps, abdominal and subscapular) were measured by a caliper in 108 subjects with DM2 who were diagnosed with the disease before the 60 years of age and compared with the same points of subcutaneous adipose tissue thickness of 112 control group subjects. Results: All points of the subcutaneous adipose tissue have been shown to be potential predictors of DM2, among which the most dominant spot was abdominal skinfold measure, OR (Odds Ratio)=1.058, CI (Confidence interval) (1.020-1.098), p=0.002,  but with a strong predictor potential of biceps  OR=1.080, CI (1.025-1.138), p=0.004, and triceps of OR 1.055 (1.016-1.096), p=0.006spots, also.

Conclusion: Centralization of adipose tissue in the region of abdomen is the strongest predictor for DM2.

Keywords: type 2 diabetes mellitus, subcutaneous fatty tissue, biceps, triceps, abdominal, subscapular



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