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This concise biography of Giovanni Battista Palletta shows how, between eighteenth and nineteenth centuries, he was among the first to trace the path of modern surgery by turning it from an empirical ability to an effective medical treatment. The article provides an overview of his clinical activity at the Ospedale Maggiore in Milan, of his scientific production and of his relationships with other eminent Italian surgeons of his times, namely Antonio Scarpa and Giovanni Alessandro Brambilla.
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Furthermore, I affirm that this article (text, illustrations, and/or tables) is original, unpublished, not under consideration by another journal, and not subject to copyright or any other of the rights that are hereby assigned to MATTIOLI 1885.